It is also known by the term sodium dodecyl sulfate. 25% aqueous as an irritant control in patch testing, and hence the results might be affected by atopic skin diathesis. In many countries SLS therefore serves as a 'control' agent for differentiating irritant skin reactions from true allergic reactions during allergy testing. Actives ingredients: Strengthening horsetail, Conditioning coconut oil, Soothing chamomile, Biodynamic nettle for scalp health, Shine-promoting rosemary and Moisture-locking aloe vera juice. Sodium laureth sulfate (SLES) is a surfactant with a similar chemical formula. The most egregious claim by far is that SLS is carcinogenic.16,32 The origin of this claim is uncertain, but it is likely to have derived from multiple misinterpretations of the scientific literature. It is used in industrial strength degreasers, floor cleaners, bubble bath and toothpastes. It, too, is a surfactant that acts as an effective cleansing and foaming agent, which is why it's often used in hair care products. Several different compounds can be used for foaming effect in SLS-free toiletries. ACADEMIC EDITOR: Timothy Kelley, Editor in Chief. Avoid products that list any of the following names in the ingredients: AI3-00356 Akyposal SDS Anticerumen Can sodium lauryl sulfate affect blood pressure. Sodium lauryl sulfate (C12H25SO4Na) is a surface-active agent used in cleaning and cosmetic products. Toothpaste with sodium lauryl sulfate leads to canker sores and other teeth related issues. The CIR report1 is also cited as supporting the claim that SLS can cause hair loss and baldness.13,16,32 The CIR report states as follows: Autoradiographic studies of rat skin treated with radiolabeled Sodium Lauryl Sulfate found heavy deposition of the detergent on the skin surface and in the hair follicles; damage to the hair follicle could result from such deposition. HSR, SRL, LBW and KEG contributed to the writing of the manuscript. Topical application of cosmetic products allows these chemicals to penetrate deep into the skin and absorbed by blood stream. Sodium Lauryl Sulfate (SLS), also called Sodium Dodecyl Sulfate (SDS), is also a chemical ingredient commonly found in personal care products from shampoos to toothpaste. Sodium Lauryl Sulfate (SLS): . There is no clinical evidence of cross-allergy between sulfonamide antimicrobials and sulfonamide non-antimicrobials, or documented evidence of cross-allergy between sulfonamide antimicrobials and Chinese herbs. Sodium Lauryl Sulfate (SLS) is an anionic surfactant naturally derived from coconut and/or palm kernel oil. According to the Environmental Working Group's Skin Deep Cosmetic Safety Database, SLS is a "moderate hazard" that has been linked to cancer, neurotoxicity, organ toxicity, skin irritation and endocrine disruption. Connect with a U.S. board-certified doctor by text or video anytime, anywhere. Expert Answers: Sodium lauryl sulfate (SLS), also known as sodium laurilsulfate or sodium dodecyl sulfate, is an anionic surfactant commonly used as an emulsifying cleaning. This review clearly demonstrates the known risks and benefits of using household cleaning products that contain SLS. Symptoms include flushing, fast heartbeat, wheezing, hives, dizziness, stomach upset and diarrhoea . This contact allergy may cause your skin to react when it is exposed to this substance although it may take several days for the symptoms to appear. and for industrial uses. Cloralstan technology formulated to kill 99.9% of germs. ago. There are now many shampoos without it. Symptoms of a sulfa allergy can include: a rash or hives on the skin itchy skin itchy eyes feeling congested swelling of the mouth or throat asthma or wheezing nausea or vomiting light-headedness. Ammonium lauryl sulfate is typically used in shampoos and body wash products and is sold as an alternative to SLS. SLS may also be listed as sodium dodecyl sulfate, sulfuric acid, monododecyl ester, sodium salt, sodium salt sulfuric acid, sodium dodecyl sulfate, aquarex me or aquarex methyl, reports the EWG. But, when sensitive skin people use these chemical ingredient items, substances like SLS can irritate the skin. the display of certain parts of an article in other eReaders. It's completely sulfate free, anti-cavity with fluoride, gently pH-balanced formula. Free of sulfates, silicone, or parabens, this hypoallergenic dandruff shampoo is ideal for sensitive skin. Sodium Lauryl Sulfate (SLS)-Free Toothpastes Many toothpastes contain sodium lauryl sulfate (SLS). It usually consists of a mixture of sodium alkyl sulfates, mainly the lauryl. Because SLS is a coconut derivative, some products containing SLS are labeled and marketed as "all natural." . A member asked: How do you classify sodium laureth sulfate. . The complexity of chemical nomenclature and wide availability of scientific research provide detailed information but lends itself to misinterpretation by the lay person. Symptoms of an allergic reaction to sulfa drugs include rash or hives, itchy skin or eyes, and swelling.. Personal care products that you use to achieve radiant and alluring skin include a bunch of chemicals. Rastogi SC. Willis CM, Reiche L, Wilkinson JD. Several different compounds can be used for foaming effect in SLS-free toiletries. Video chat with a U.S. board-certified doctor 24/7 in less than one minute for common issues such as: colds and coughs, stomach symptoms, bladder infections, rashes, and more. Sodium coco sulfate, a coconut derivative, has a foaming action without the potential for formation of the carcinogenic chemical 1,4-dioxane. For the surfactant sodium lauryl sulfate (SLS), this has resulted in a misunderstanding of the environmental health impact of the chemical and statements in the media that are not scientifically supported. This means that while SLS is moderately toxic to aquatic life in its raw material form, product formulations that contain dilutions of SLS are not necessarily moderately toxic and, in fact, can be nontoxic to aquatic life. SLS is present in most body washes, soaps, shampoos, toothpastes and laundry detergent. CAS#: 151-21-3 . The Cosmetic Ingredient Review reports that SLS, SLES and ALS are irritants at concentrations of 2 percent or greater, and recommends that cosmetic products should not contain concentrations greater than 1 percent. ; Sarah Schmidt; March 2009, MSNBC; Ditching Shampoo -- A Dirty Little Secret; Melissa Dahl; April 2009, "Compendium of Continuing Education in Dentistry"; The Effect of Sodium Lauryl Sulfate on Recurrent Aphthous Ulcers: A Clinical Study; L. Chahine, et al. Denaturation and proteolysis behavior. Upon submission manuscript was subject to anti-plagiarism scanning. Sodium lauryl sulfate is found in products such as engine degreasers, floor cleaners, car wash soaps, toothpastes, shampoos, shaving foams, dissolvable aspirins, and bubble baths. As in the CIR report, the researchers of this study38 identified the deposition of SLS on the root sheath of the hair follicle but did not draw conclusions about the effects of this deposition on the hair. Chest tightness. It is important that . According to the National Library of Medicines TOXNET database, SLS is not classified as a known or suspected mutagen, reproductive or developmental toxicant, neurotoxicant, or endocrine disruptor.33. Piret J, LaForest G, Bussires M, Bergeron MG. Subchronic (26- and 52-week) toxicity and irritation studies of a novel microbicidal gel formulation containing sodium lauryl sulfate in animal models. Zheng YJ, Chen L, Chen YP, Huang R. Acute toxicity of sodium dodecyl sulfate (SDS) on selected aquatic organisms. What is the definition or description of: dalteparin sodium allergy? hello. In the study by Birt et al.35, SLS was used as a vehicle to process the agent being tested. Tekba F, Uysal Y, Our R, et al. Each human health and environmental claim is assessed against peer-reviewed scientific evidence for accuracy and validity. lately i have had no energy. All Material Provided within this Website is for Informational and Educational purposes only, And is not to be construed as Medical advise or Instruction. It's used in a variety of products such as food thickeners, toothpaste, and. For decades, this chemical has been developing a negative reputation with consumers because of inaccurate interpretations of the scientific literature and confusion between SLS and chemicals with similar names. All versions of Crest toothpaste contain Sodium Lauryl Sulfate (SLS). Also, Monosodium glutamate (msg) is an additive in some foods, but is not related to "house allergy" in any way. Carcinogenic substances have the potential to cause cancer, although it is uncertain how such carcinogens could affect your body when they are not ingested or eaten. In this case, the dissemination of misconstrued results not only provided a disservice to the general public but also caused serious repercussions for the scientific researchers. Robinson, et al. You may notice problems with Therefore, the two cannot react to form a nitrogen-containing nitrosamine. SLS is a cleaning agent and surfactant found in many consumer products, according to Chemical Safety Facts Because of it's cleaning power, SLS is prevalent in toothpaste It not only cleans but also helps remove food debris stuck in your mouth and teeth Avoid contact with skin and eyes. surfactant, media claims, product formulation, ingredient safety review. that it can cause severe dermal sensitization. Background. Only ships with $35 orders. This is an open-access article distributed under the terms of the Creative Commons CC-BY-NC 3.0 License. What does this study add? What happens if i take a medicine/cream that contains sodium cetostearyl sulphate if i have an allergy to sufla? The names and labeling of different chemical compounds in toiletries can be confusing. SLES is an inexpensive and very effective foaming agent. Sodium lauroyl sarcosinate is only similar to sodium lauryl sulfate in that they're both surfactants, but that's about where it ends. It is well-known for causing skin discomfort, which can lead to altered skin barrier function and water-loss. Sodium laurel sulfate, also spelled sodium lauryl sulfate, is closely related to SLS. As far as allergies go, Nazarian says when a patient comes in with a potential contact allergy, sodium lauryl sulfate is one of the ingredients that they will test for, but it's more of an irritant than it is an allergy. Even in large quantities, sulfites usually don't cause problems in people without allergies and asthma. Its recommended to check with the allergist before buying any new product launched in the market. Furthermore, it should be noted that the anatomy of the eye renders direct exposure of the lens to SLS impossible, as it is deep within the eye protected by the cornea, and therefore, not vulnerable to exposure through typical consumer product usage.22,23 As such, a causal relationship between SLS in consumer products and cataract formation is not scientifically supported. . Sodium Coco Sulfate contains Sodium Lauryl Sulfate. Allen specializes in travel, health/fitness, animals and other topics. DB00815. Dermal toxicity studies demonstrate that 24-hour exposure to a 12% (w/w) solution of SLS can increase the transepidermal water loss of the stratum corneum the outer most layer of the skin and cause mild yet reversible skin inflammation.24,25 Human patch tests (typically a 24-hour exposure) confirm that SLS concentrations >2% are considered irritating to normal skin.2,26,27 Dermal irritation also tends to increase with SLS concentration and the duration of direct contact.2 In reality, dermal exposure to SLS in cleaning products is more likely to last a matter of minutes rather than hours.9, Cleaning products that contain SLS have the potential to be dermal irritants if not formulated properly, but products that contain SLS are not necessarily irritating to the skin.28,29 Proper formulation development includes strategies for mitigating irritation (like adding cosurfactants) and can produce products with SLS that are mild and nonirritating to the skin. Sodium laureth sulfate ( SLES ), an accepted contraction of sodium lauryl ether sulfate ( SLES ), also called sodium alkylethersulfate, is an anionic detergent and surfactant found in many personal care products ( soaps, shampoos, toothpaste, etc.) The small amount of sulfate in your shampoo and body wash should not cause Sulfa allergy is usually secondary to antibiotics such as bactrim (sulfamethoxazole and trimethoprim). De Jongh CM, Verberk MM, Withagen CE, Jacobs JJ, Rustemeyer T, Kezic S. Stratum corneum cytokines and skin irritation response to sodium lauryl sulfate. Your symptoms should be addressed by your doctor. For these, please consult a doctor (virtually or in person). Foaming Agents The foaming properties of toothpaste depend on a chemical known as sodium lauryl sulfate, which in most cases is known to irritate inside and outside the mouth. There is no scientific evidence supporting that SLS is a carcinogen.33,34 SLS is not listed as a carcinogen by the International Agency for Research on Cancer (IARC); U.S. National Toxicology Program; California Proposition 65 list of carcinogens; U.S. Environmental Protection Agency; and the European Union. The concentration of SLS found in consumer products varies by product and manufacturer but typically ranges from 0.01% to 50% in cosmetic products1,2 and 1% to 30% in cleaning products.3,4 SLS can be synthetic or naturally derived. Lewis MA. Science-based formula - Our plant-derived formula is made with sniffing deliciously pure essential oils and USDA certified organic surfactants that clean and protect delicate clothing; Free from Sulfate harsh chemicals, toxins, dyes, phthalates, and parabens. This compound is the sodium salt of the 12-carbon an organosulfate. This means that while SLS as a raw material at 100% concentration may have a LD50 of >5,000 mg/kg, formulations that contain diluted or lesser concentrations of SLS are not necessarily toxic and can even be nontoxic. Chronic and sublethal toxicities of surfactants to aquatic animals: a review and risk assessment. Your patch test result indicates that you have a contact allergy to sodium lauryl sulfate. Sodium lauryl sulfate allows shampoos and other body products to foam. Use explosion-proof equipment. toilet cleaners . According to Environmental Working Group (EWG) 1 in 5 cosmetic products may contain cancer causing agents. Cromolyn sodium is the active ingredient in anti-allergy eye drops and nasal spray. Consult your Physician or a Qualified Health Professional on any matters regarding your health and well-being or on Any opinions expressed within this Website. Ocular irritation has been induced in vivo using SLS concentrations equivalent to a rinse-off personal care product containing 20% SLS.17 However, this was achieved after the eyes of laboratory animals were repeatedly exposed to 0.5 mL of shampoo for 14 days.17 While SLS is useful in studying the formation and repair of cataracts in laboratory settings, studies of this nature are not appropriate for assessing the risk of human exposure to SLS in cleaning products. Indeed, the non-foaming toothpaste caused significantly fewer ulcers than the non-SLS alternative detergent, CAPB, which in turn caused significantly fewer ulcers than the SLS toothpaste. Other: Additional causes could be physical irritation from dentures, contact allergy to denture components (contact stomatitis) or oral hygiene products (Sodium Lauryl sulfate in toothpastes), gastroesophageal reflux disease, low levels of thyroid hormones, certain antihypertensive medications, changes in salivary composition, tongue thrusting . One example of an irritant agent is sodium lauryl sulfate (SLS), a detergent that has been extensively studied with regard to causing irritant contact dermatitis. SCS contains SLS. The acute oral toxicity of individual ingredients and formulated products is measured in terms of the median lethal dose (LD50), which indicates the quantity by weight (typically in milligrams of substance per kilograms of body weight) required to kill half of the laboratory animals receiving that dose. U.S. Food and Drug Administration (FDA), 21 C.F.R. Sodium lauryl sulfate is one such chemical substance, which can irritate your skin. Cater KC, Harbell JW. could i be absorbing it. Sodium Lauryl Sulfate (SLS) is actually the parent chemical that is modified to make Sodium Laureth Sulfate (SLES). I have an allergy to sulfur. It is an anionic surfactant used in many cleaning and hygiene products. As of 2015, no scientific evidence has been produced to suggest that dermal exposure to SLS causes hair loss. It is often claimed that SLS absorbs into the blood stream, builds up in the heart, liver, lungs and brain, and causes damage.13,16 Claims of this nature often cite the Cosmetic Ingredient Review (CIR) Final Report on the safety of SLS, which contains an extensive review of the absorption and excretion of SLS in humans and animals.1 However, the CIR concludes that while SLS can be absorbed through the skin when applied directly, the majority of the material remains in or on the skin surface. $5.29. Review of the human and environmental toxicity profiles of SLS is warranted to elucidate the known risks and benefits of using SLS in household cleaning product formulation. JLM is a scientific writer and revised the manuscript to its final version. Is is also 100% natural, 70% organic and Free from wheat, dairy, soy, common allergen nut oils and is suitable for vegans These fatty alcohols undergo oxidation to produce fatty acids, which are degraded by -oxidation and fully mineralized and incorporated into the biomass.45 Thus, the decomposed by-products of SLS are benign to the environment. The report goes on to say that high concentrations of SLS may affect the hair, but no evidence is presented to show that SLS exposure causes hair loss. Because SLS is a coconut derivative, some products containing SLS are labeled and marketed as "all natural. I know of no one who is allergic to sulfate. Mandal K, Chakrabarti B, Thomson J, Siezen RJ. Cosmetic Ingredient Review (CIR) Final report on the safety assessment of sodium lauryl sulfate and ammonium lauryl sulfate. To learn more, please visit our. When purchased online. Allergic contact dermatitis, on the other hand, is a result of your body's exaggerated response to otherwise harmless substances in beauty products. Sulfa drugs, specifically sulfonamide antimicrobials, may cause allergy in approximately 3% of the population. Great number of allergic reactions to sodium lauryl sulfate (6.4%) was observed." That's 15 people among 242. would this allergy mean i am allergic to sodium laureth sulfate found in body wash? Toothpaste Allergy Symptoms Regularly toothpaste hypersensitivity is misdiagnosed or not reported. Effendy I, Maibach HI. There is no discussion of hair loss. Ecotoxicity studies have determined that a surfactant concentration of 0.5 mg/L of natural water would be essentially nontoxic to fish and other aquatic life under most conditions.42 It is suggested, however, that chronic toxicity of anionic surfactants occurs at concentrations as low as 0.1 mg/L.40. ; July 2010, "Journal of AOAC International"; Occurrence of 1,4-dioxane in Cosmetic Raw Materials and Finished Cosmetic Products; R.E. For example, sodium chloride (table salt) has an LD50 of 3,000 mg/kg, making it moderately toxic by definition.31. Products with the EWG VERIFIED mark have met the . Like sodium lauryl sulfate (SLS), coconut diethanolamide can break down skin's oily barrier layer and dry it out, but certain people develop more intense allergic reactions to it. An article written by Birt et al.36 is commonly cited as supporting the carcinogenicity claim for SLS. Sodium laureth sulfate, also commonly referred to as SLS or sodium lauryl ether sulfate, is a key ingredient in many toiletry products. HealthTap uses cookies to enhance your site experience and for analytics and advertising purposes. Exposure of this sort is not ordinarily experienced through normal cosmetic use. This ingredient's score is higher if used in products that are inhalable (e.g., sprays, powders) because of respiratory concerns. According to Mercola.com, although SLS is derived from coconuts, it is contaminated with a toxic byproduct during the manufacturing process. All antibiotics can cause allergic reactions such as hives and side effects such as diarrhea, upset stomach, etc. A gentle yet potent combination essential oils including tea tree, aloe vera, Moroccan argan oil, and lavender, work together to cleanse, balance, hydrate, and revive lifeless locks. However, some people with a sensitivity to SLS can experience allergic reactions to this compound. An allergy to SLS is actually more likely to be a sensitivity to this ingredient. SLS that is absorbed into the bloodstream is quickly metabolized by the liver into more water-soluble metabolites that are rapidly excreted through the urine, feces, and sometimes expired breath.1,22,23,37 There is no evidence in the CIR report or in the scientific literature at large that supports the accumulation of SLS in vital organs and associates it to systemic toxicity or vital organ damage.22,23,33 As such, accusations that SLS will bioaccumulate in humans and cause organ damage are inaccurate. SLS - Sodium Lauryl Sulfate I read online about how some people are allergic to SLS - Sodium Lauryl Sulfate, and how their heads would itch, and breakout, and it would also affect the rest of their bodies from the shampoos that they would use, and that described what I was experiencing. Your safest bet is to avoid shampoos with SLS. FUNDING: JLMs work as a scientific writer for this manuscript was funded by Seventh Generation. This may confuse you if you are looking for SLS-free products to reduce the risk of allergic reactions. Wash off immediately with soap and plenty of water removing all contaminated clothes and shoes. Immunocytochemical demonstration of reduced Cu,Zn-superoxide dismutase levels following topical application of dithranol and sodium lauryl sulphate: an indication of the role of oxidative stress in acute irritant contact dermatitis. // Leaf Group Lifestyle, Allergic Reaction to Hair Product: Scaly Dry Rash on Neck, How to Know if You're Allergic to Tattoo Ink, "International Journal of Toxicology"; Final Report of the Amended Safety Assessment of Sodium Laureth Sulfate and Related Salts of Sulfated Ethoxylated Alcohols; V.C. A study published in 1998 by the European Journal of Dermatology is also cited as supporting claims that SLS causes hair loss.38 This study investigates the effects of oxidative stress on skin irritation and uses SLS as an experimental irritant. ; May/June 2001, Mother Nature Network; Safe Shampoo? Firstly, the European Chemicals Agency (ECHA) classifies SLS as: "harmful if swallowed, causes serious eye damage, is harmful to aquatic life with long lasting effects, is a flammable solid, is harmful if inhaled, causes . CAMB and JLM jointly made critical revisions to the manuscript. Birt DF, Lawson TA, Julius AD, Runice CE, Salmasi S. Inhibition by dietary selenium of colon cancer induced in the rat by bis(2-oxopropyl) nitrosamine. SLS may make your skin sensitive even if it wasn't sensitive before. This ingredient's score is higher if used in products intended for use around the eyes due to increased risk of absorption. 13, 16 A sensitizer is a substance that causes hypersensitivity through an allergic or . Key Takeaways. An SLS allergy will heighten the sensitivity and cause . No evidence supporting the carcinogenic effect of SLS was reported. Few researchers say that products that include SLS have carcinogenic agents, which can trigger cancer. If you are allergic to sulfa there is a small cross reactivity to sulfate. Table 1 summarizes the available toxicology data on SLS. Your patch testing results indicate that you have a contact allergy to Sodium Lauryl Sulfate. Undiluted SLS can cause skin and eye irritation, as well as nausea, vomiting and diarrhea if ingested, according to the National Institute for Occupational Safety and Health. Typical symptoms include redness . The U.S. Consumer Product Safety Commission (CPSC;16 C.F.R. There are also reported cases of it being responsible for the swelling of the face and arms. Nitrosamines contain two nitrogen atoms, but neither SLS nor formaldehyde contain nitrogen atoms. Consumer Product Safety Commission (CPSC). Use and disposal of cleaning products release SLS into the environment via household wastewater systems. This can be very irritating to the eyes. Unfortunately, it can cause side effects such as mouth ulcers, canker sores, allergic reactions, and even break down the enamel on your teeth. Read More :- What is laundry detergent Other claims denouncing SLS as a carcinogen point to a chemical reaction between SLS and formaldehyde that creates nitrosamines as a by-product.32 However, it is not possible for SLS and formaldehyde to react and form a nitrosamine. Sodium lauryl sulfate: This is a foaming agent that guides in expelling microorganisms and debris from the teeth and in addition cleanses the teeth. Some people get mouth ulcers from SLS in toothpaste. i am allergic to sulfa and i need to know if my shampoo and body wash are causing me problems.
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